Refueling the Failing Heart
نویسندگان
چکیده
منابع مشابه
Pharmacogenomics and the Failing Heart
n Samuel Beckett’s play, Waiting for Godot, the characters ait by a country roadside for a person named Godot, who ever arrives (1). Godot’s conspicuous absence throughout he play has fostered a variety of different religious, philoophical, and psychoanalytical interpretations, and has led o the use of the phrase “waiting for Godot” as an expression or waiting for someone or something that will...
متن کاملMyocardial Recovery and the Failing Heart
Medical and device therapies that reduce heart failure morbidity and mortality also lead to decreased left ventricular volume and mass and a more normal elliptical shape of the ventricle. These are due to changes in myocyte size, structure, and organization that have been referred to collectively as reverse remodeling. Moreover, there are subsets of patients whose hearts have undergone reverse ...
متن کاملDefective lipid metabolism in the failing heart.
The metabolism of long chain fatty acids was investigated in the failing heart of guinea pigs with chronic constriction of the ascending aorta. Homogenates prepared form failing hearts exhibited (a) a decreased capacity to oxidize palmitic acid (failure = 0.50 +/- 0.06 mumole/g of protein per 20 min; control = 1.09 +/- 0.10); (b) a reduced level of carnitine, a myocardial constituent which serv...
متن کاملCirculatory assistance for the failing heart.
Although coronary care units have been successful in reducing the in-hospital mortality after acute myocardial infarction, this is largely a result ofpreventing and treating dysrhythmias. Thefailing myocardium remains a therapeutic challenge and current medical therapy disappointing. Methods ofproviding the heart with mechanical support are described and indications and contraindications to the...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2018
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2018.08.002